Diarrheal diseases are one of the important causes of death and disability in developing countries. Masrara has reduced the mortality caused by diarrhea, but it has no effect on the duration and severity of the disease. Many studies have suggested the use of probiotics to treat acute diarrhea as an adjunctive treatment. The present research has been conducted to review the effects of bacterial and fungal probiotics on acute diarrhea in children.
This study was conducted as a clinical trial on 09 two- to five-year-old children who were referred to the Kashan Children's Clinic in 2001 with a complaint of diarrhea in Harad Rabkari and received outpatient treatment. These children were randomly divided into groups of 30 people. One group was subjected to standard treatment with rehydration oral solution plus bacterial probiotics in the form of Kidi Lact tablets once a day, and two groups were given the addition of Karachi Karachi probiotics, Sherkel Kerr Sarrdgfar 159 mg once a day, and the rehydration group was given standard therapy once a day. Do not compare with placebo. The duration of treatment with probiotic or placebo was 5 days.
The findings of the study show that there is no significant difference in the three study groups regarding age, sex, number of times and duration of diarrhea before referral. Miraniin Merdet Eserhal's recovery from sarcoma was improved in the first group of probiotic bacteria (18.9 days, in the second group of fungal probiotics, 3289 days, and in the placebo group, 9.8 days). There was a significant difference in the duration of diarrhea after treatment in the three groups. It was observed that the best effect in reducing the duration of diarrhea was related to the bacterial probiotic and the lowest effect was related to the placebo.
The results of this study and other studies show that the use of probiotics in children's diarrheal diseases can be effective in shortening the period of diarrhea.
Keyword:
Diarrhea, probiotics, children
Introduction:
Diarrheal diseases are one of the main causes of mortality and morbidity in the developing countries. ORS (oral rehydration solution) has turned up to decrease diarrheal mortality, but has left no effect on the duration and severity of the disease. Different studies have focused on the use of probiotics as a supplementary treatment for acute diarrhea. This current study is to evaluate the effect of bacterial and yeast probiotics in children with acute diarrhea.
Material and Method:
This clinical trial was conducted on 90 two-five years old children with acute watery diarrhea referred to pediatrics clinic in 2013 as outpatient cases. These children were divided randomly into three different groups of thirty. One group was under standard treatment with oral dehydration solution in addition to bacterial probiotics in form of Kidilact once a day. The second group, in addition to ORS, received yeast probiotics in form of Argopharm 250mg once a day. The third group received standard rehydration therapy along with placebo. Treatment with probiotics or placebo lasted for 5 days.
Result:
Our findings demonstrated no significant difference in the three groups in terms of age, sex, frequency, and duration of diarrhea before treatment. Mean durations of diarrhea from commence of treatment to recovery were 2.80, 3.17, and 4.43 days for the first (bacterial probiotic), the second (yeast probiotic), and the third (placebo) groups, respectively. A significant difference was revealed among the three groups in terms of diarrhea duration. The bacterial probiotic group had the best effect in reducing diarrheal length, while the placebo group had the least effect in this respect.
Conclusion:
Findings of the current study and those of other studies confirm that application of probiotics in pediatric diarrheal diseases can be effective in minimizing course of diarrhea. According to our study, bacterial probiotic appeared more effective than the yeast probiotics in this regard.
Keywords: Diarrhea, Probiotic, Children